PRESS RELEASE

May 10, 2006

Advanced Biomaterial Systems Receives Additional US Patent for Plexis® Percutaneous Delivery of Biomaterials

Chatham, NJ – May 10, 2006
Advanced Biomaterial Systems, Inc. (ABS) announced today that it has been issued U.S. Patent No. 7,029,163, apparatus and methods for mixing and delivering biomaterials into skeletal structures. This patent covers technology integrated in ABS Plexis® Bone Void Filling System and follows U.S. Patent No. 6,984,063 issued to ABS earlier this year. Plexis® is an integrated system used to mix and deliver ABS Concert® Spine VR radiopaque bone cement in percutaneous procedures such as vertebroplasty and kyphoplasty.

“ABS continues to strengthen and expand its intellectual property platform of patented delivery technologies and proprietary biomaterials. We now have a total of eleven U.S. and International patents covering our integrated mixing and delivery devices,” states CEO Pete Carr.

About Advanced Biomaterial Systems (www.advbiomat.com)

Advanced Biomaterial Systems, Inc. develops proprietary biomaterials and delivery systems designed to advance procedure outcomes and patient safety. ABS delivery technology includes Plexis® Bone Void Filling System for percutaneous procedures and twistOR PrePack® Mixing and Dispensing System for total joint replacement procedures. ABS biomaterials include the Concert® family of bone cements: Concert® Spine VR Radiopaque Bone Cement approved for use in vertebroplasty and kyphoplasty procedures, Concert® Bone Cement approved for use in the fixation of prosthetic devices to living bone, and Concert® Cranioplast approved for use in repairing cranial defects.

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